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One biotech is looking to lessen antipsychotic-induced weight gain, despite...

Response Pharmaceuticals believes its experimental drug can lessen the persistent weight gain associated with antipsychotics. In a new pilot study, the company assessed RDX-002 in 20 healthy people....

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‘We’re good’ on weight loss: Biopharmas turn to muscle with new obesity drugs

SAN ANTONIO — It took decades to get to the GLP-1 breakthrough in obesity treatment. Now, the biopharma industry is clamoring over the field's next frontier: staving off the losses in muscle or lean...

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Acadia lands $150M sale of rare pediatric PRV

Acadia Pharmaceuticals has sold its priority review voucher for $150 million, the company said Tuesday, but did not disclose the buyer. The FDA granted Acadia the rare pediatric PRV in March ...

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Novo unveils new cardiometabolic data as it reports solid third-quarter profits

Novo Nordisk disclosed several key updates from its cardiometabolic and hematology pipelines Wednesday as the drugmaker revealed its third-quarter profits edged out expectations. First up, the Danish...

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New Trump era could be a boon for biopharma M&A, dealmaking

As former President Donald Trump returns to power — the Associated Press projected his presidential victory Wednesday morning — the biopharma industry may see the door open wider for more dealmaking,...

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At this year's ObesityWeek, GLP-1s aren’t the only talk of the town

SAN ANTONIO — As the GLP-1 class has taken over in recent years, a once-fringe conference has come into the spotlight for the biopharma industry. ObesityWeek, which started in 2013, attracted more than...

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Biotech industry worries over potential for RFK Jr. ally as FDA pick

US presidential election winner Donald Trump has promised to let his ally Robert F. Kennedy Jr. “go wild” on drug and food policy. While Kennedy’s exact role in a potential Trump administration is...

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MacroGenics pauses development of ADC; Cellectis deprioritizes CAR-T

Plus, news about Tango Therapeutics, Endo, Neurogene and Century Therapeutics: MacroGenics stopped dosing patients in ADC trial: After three patient deaths in a Phase 2 prostate cancer drug trial for...

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CVS names Aetna head, plans more pharmacy closures as new CEO takes over

In his first quarter leading CVS Health, CEO David Joyner laid out the initial steps he’s taking to rightsize the company, as challenges continue to plague its insurance business. As part of those...

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Studies show how once-obscure DNA circles drive cancer, and maybe even how to...

Scientists have unveiled a strategy for targeting a vulnerability in tiny circles of floating DNA that can drive aggressive cancers. These circles — known as extrachromosomal DNA, or ecDNA, because...

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Q&A: GSK’s CEO Emma Walmsley on the new Trump administration, trust, AI and...

Despite the rise of a vaccine skeptic in the campaign of US presidential election winner Donald Trump, GSK CEO Emma Walmsley believes her company can work “constructively” with the incoming...

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California voters say yes to restrictions around 340B spending

California voters supported a state ballot measure on Tuesday that would increase oversight around the 340B federal drug discount program. According to unofficial results, 51.5% of voters said yes to...

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Sarepta discontinues work on next-gen exon-skipping drug for Duchenne

Sarepta Therapeutics is stopping development of vesleteplirsen, an experimental exon 51-skipping therapy for Duchenne muscular dystrophy patients with certain mutations. It's also halting work on all...

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Moderna reports $10M in first RSV sales, a slow start for new vaccine

Moderna revealed the consequences of its late start in the market for RSV vaccines, reporting just $10 million in third-quarter sales from the new shot. Those numbers are a fraction of the $600 million...

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Joe Jimenez's latest Aditum company lines up T cell engager from China

Joe Jimenez's Aditum Bio, an investment firm that builds companies around in-licensed assets, is going after one of the hottest new areas for its latest startup. The Oakland, CA-based firm is setting...

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Arcus backs TIGIT combo by offering glimpse at positive data from axed trial

Arcus Biosciences unveiled data from a terminated late-stage study of its TIGIT and PD-1 drug combo that it says supports its decision to take the approach forward in a different lung cancer setting....

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Gilead beats Covid drug sales forecasts, takes $1.75B hit on Trodelvy study fail

Gilead said its Covid-19 antiviral Veklury had $692 million in third-quarter sales, far more than the $270 million Wall Street analysts had projected. Gilead’s shares {$GILD} were up 3% in after ...

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How Menlo Ventures thinks AI in health tech is going to be commoditized

While there’s a lot of potential for AI in health tech, it will soon be commoditized, investor Greg Yap told Endpoints News in an interview on the sidelines of the HLTH conference in Las Vegas ...

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Avid Bioservices to be sold to private equity firms for $1.1B

After a year of customer pullbacks, biologics CDMO Avid Bioservices will be taken private by GHO Capital Partners and Ampersand Capital Partners in a deal worth $1.1 billion. “In evaluating this...

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Nobel winner Demis Hassabis talks next steps for AI in biology

LONDON — Demis Hassabis is pursuing one of the boldest efforts of bringing AI into biotech, building out the Alphabet-backed startup Isomorphic Labs over the past three years. In an exclusive sitdown ...

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